HomeAnswersInfectious DiseaseshivCan I get HIV despite a negative antigen test?

Is there any medicine to prevent HIV?

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Medically reviewed by

iCliniq medical review team

Published At April 29, 2024
Reviewed AtMay 9, 2024

Patient's Query

Hello doctor,

I am a 38-year-old male; I went to a spa and got a massage from a girl. Things got heated, and we got intimate. We had coitus using a condom. But later, I realized that it was torn. I am scared that I might get HIV from her. I did not know about her medical history. This happened three weeks ago. Yesterday, I did an antigen test, and it came back negative. I am worried that I can still get HIV. Please help.

Thank you.

Hello,

Welcome to icliniq.com.

I can understand your concern. Please let me know if you have taken post-exposure prophylaxis. As per WHO (World Health Organisation) guidelines, PEP (post-exposure prophylaxis) means taking medicine to prevent HIV (human immunodeficiency virus) after a possible exposure. PEP should be used only in emergencies and must be started within 72 hours after a recent possible exposure to HIV. I would suggest you take the tablet Emtricitabine or Tenofovir sulfenamide daily for 30 days and the tablet Dolutegravir once daily for 30 days.

However, since you appeared to have crossed the 72 hours post-exposure, PEP may not be valid for you. HIV tests might be required. Detectable viremia does not develop until approximately 10 to 15 days after infection, and even the most sensitive immunoassays do not give a positive result until five days after that. The initial negative immunoassay and virologic tests can be misleading, and if the clinical suspicion for recent HIV exposure is high, repeat testing is done one to two weeks later. I would also suggest you test for other sexually transmitted infections (STIs) in the form of in a laboratory near you. Please revert after these tests.

I hope this helps you.

Thank you.

Regards.

The Probable causes:

Sexual exposure.

Investigations to be done:

HIV Tests - 1) Fourth-generation assay: Detect specific antibodies and P24 HIV antigens.

2) Rapid test: Use blood or saliva to detect an HIV infection within hours.

3) Polymerase-chain-reaction (PCR): This can be a diagnostic or a confirmative test for HIV infection and can provide information about the viral load.

B) STI package tests such as syphilis, gonorrhea, Hepatitis B and C, herpes, chlamydia, etc., blood tests.

Differential diagnosis:

Sexually transmitted diseases.

Treatment plan:

After HIV and STI tests, initiate appropriate medications.

Regarding follow-up:

After prescribed tests.

Preventive measures:

Further sexual exposure or to unsafe intravenous practices.

The Probable causes

Sexual exposure

Investigations to be done

A) HIV Tests - 1) Fourth-generation assay: detect specific antibodies and P24 HIV antigens. 2) Rapid test: Use blood or saliva to detect an HIV infection within hours. 3) Polymerase-chain-reaction (PCR): This can be a diagnostic or a confirmative test for HIV infection and can provide information about the viral load. B) STI package tests such as syphilis, Gonorrhea, Hepatitis B and C, Herpes, Chlamydia, etc. Blood tests

Differential diagnosis

Sexually transmitted diseases.

Treatment plan

After HIV and STI tests initiate appropriate medications.

Preventive measures

Further sexual exposure or to unsafe intravenous practices.

Regarding follow up

After prescribed tests.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Shubadeep Debabrata Sinha
Dr. Shubadeep Debabrata Sinha

Infectious Diseases

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