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Can avoiding nephrotoxic agents help prevent further damage to the kidneys?

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Published At April 23, 2024
Reviewed AtApril 23, 2024

Patient's Query

Hello doctor,

Please review my blood test results. The chemistry test report indicates abnormalities, with an acute kidney injury warning stage, and the complete blood count report is borderline. I have been experiencing ongoing tummy pain for three months, which tends to worsen at night. Two years ago, I underwent a hysterectomy for adenomyosis, so I have been considering if there might be a related connection. I am currently using HRT (hormone replacement therapy) gel and taking Ibuprofen for pain.

Thank you.

Hello,

Welcome to icliniq.com.

I am sorry to hear about your blood reports. Your blood test results indicate two main concerns: an abnormal chemistry test suggesting acute kidney injury (AKI) and a full blood count that is borderline. Let us discuss what this might mean for your health and what steps should be taken next.

  1. Acute kidney injury (AKI) warning stage: Acute kidney injury is a condition where your kidneys suddenly are unable to filter waste products from your blood. When this occurs, dangerous levels of waste may accumulate, and your blood's chemical makeup may get out of balance. The warning stage suggests that your kidney function has declined rapidly, which could be due to various factors such as dehydration, certain medications, an obstruction in your urinary tract, or an underlying illness.
  2. Borderline full blood count: A full blood count (FBC) measures the concentration of red blood cells, white blood cells, and platelets in your blood. A borderline result indicates that one or more of the measured components are at the lower or higher edge of the normal range. This could be due to a range of conditions, from mild infections to more serious blood disorders.

Given these findings, it is important to take the following steps:

  1. Further evaluation: Additional tests may be necessary to determine the cause of the AKI and the specifics of the borderline full blood count. This might include urine tests to check for signs of kidney damage or infection, imaging studies such as ultrasound to view the kidneys, and possibly a kidney biopsy if the cause of the injury is not clear.
  2. Review medications and supplements: Some substances can harm the kidneys, especially if taken in large amounts or your kidneys are not functioning well. Provide a list of all medications, supplements, and over-the-counter drugs you take to your healthcare provider.
  3. Hydration and diet: Ensure you are well-hydrated, as dehydration can contribute to AKI. Depending on the cause and severity of the kidney injury, you may need to modify your diet, such as reducing salt, protein, and potassium intake.
  4. Monitor and manage blood pressure: High blood pressure can be both a cause and a consequence of kidney damage. Keeping it under control is crucial.
  5. Avoid nephrotoxic agents: Certain substances can further damage the kidneys, such as NSAIDs (nonsteroidal anti-inflammatory drugs, for example, Ibuprofen), some antibiotics, and contrast dyes used in imaging tests.
  6. Address underlying conditions: If the AKI is due to another condition, such as diabetes or high blood pressure, it is crucial to manage these effectively.
  7. Regular monitoring: Follow-up blood tests will be necessary to monitor your kidney function and full blood count.
  8. Consult a specialist: Depending on the severity of the AKI and the full blood count results, you may need to see a nephrologist (a kidney specialist) or a hematologist (a blood specialist). It is important to address these results promptly with your healthcare provider, who can provide a more specific treatment plan based on the full context of your health and the detailed results of your tests.

Thanks for using icliniq, and have a nice day.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Vandana Andrews
Dr. Vandana Andrews

General Practitioner

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